Google
Trusted Resources: News & Events
Latest announcements and gatherings
Randomized Trials Needed to Assess Benefits of Salmonella Vaccines in SCD Patients, Study Says
Randomized controlled trials are needed to examine the benefits of vaccinating people with sickle cell disease (SCD) against salmonella infections, which can be particularly fatal to children with the disease, a study says.
The review study, “Vaccines for preventing invasive salmonella infections in people with sickle cell disease,” was published in the Cochrane Database of Systematic Reviews.
Among people with SCD, mortality is highest in children, with a rate of between 2 percent and 30 percent in the first five years of life. Many of these deaths are caused by severe infections, to which children with SCD are more susceptible.
The sickle shape of SCD red blood cells makes them more prone to getting stuck inside small blood vessels, including in the spleen, which can block the blood flow through this organ and cause a condition referred to as splenic sequestration.
+myBinderRelated Content
-
Immunoglobulin G Responses Against Falciparum Malaria Specific Antigens are Higher in Children with Homozygous Sickl...Background: High Immunoglobulin G (IgG)...
-
Kids with sickle cell disease aren’t receiving key vaccines, Michigan study findsA significant proportion of children w...
-
Hospitals See No Link Between US Opioid Crisis and Patients’ Use of Treatment, Study ReportsThe U.S. opioid epidemic is not linked t...
-
Sickle cell disease is associated with higher mortality among patients hospitalized with ischemic bowel diseaseBackground: Sickle cell disease (SCD) i...
-
Study challenges view that sickle cell trait increases mortality riskSurprising findings from a study of heal...
-
The ‘Voice of Lagos’ is silent: Entertainer Tosyn Bucknor dies at 37Nigerians are paying tribute t...
-
Sickle cell trait may not increase the risk of deathPeople who carry a gene for sickle cell ...
To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences. More Information
The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.
Powered by
Support for this site is provided by
This platform is made possible through a partnership with the Sickle Cell Disease Association of America, Inc. (SCDAA) and its member organizations. SCDAA's mission is to advocate for people affected by sickle cell conditions and empower community-based organizations to maximize quality of life and raise public consciousness while advancing the search for a universal cure.